Treatment of disseminated granuloma annulare with fumaric acid esters

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Treatment of disseminated granuloma annulare with fumaric acid esters

BACKGROUND Granuloma annulare is a granulomatous disease of unknown etiology. Various therapies have been tried in disseminated granuloma annulare (DGA), including corticosteroids, several variants of psoralen plus ultraviolet-A radiation, ultraviolet- A1 radiation, systemic retinoids, and dapsone, with variable success. We report a patient with recalcitrant DGA who was treated with fumaric aci...

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Treatment of disseminated granuloma annulare with low-dose fumaric acid.

While localized variants of granuloma annulare are typically self-limited, disseminated granuloma annulare tends to be chronic and often therapy-resistant. Treatment with fumaric acid esters is effective for severe forms of psoriasis. Disseminated granuloma annulare has also been reported to respond to fumaric acid esters. We treated 8 patients (mean age 64.2 years; 4 men, 4 women) with low-dos...

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Disseminated granuloma annulare: study on eight cases.

Granuloma annulare (GA) is classified as localized, generalized/disseminated, subcutaneous, and perforating types. The studies show connection with diabetes mellitus, lipidic metabolic disorders, malignant diseases, thyroid disorders, infections (HBV, HCV, HIV). We performed a retrospective study between 2010-2011, regarding disseminated GA (GAD), and the relationship between GAD and other como...

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Successful treatment of recalcitrant cutaneous sarcoidosis with fumaric acid esters

BACKGROUND Sarcoidosis is a multisystem disease of unknown origin characterized by the formation of noncaseating granulomas, in particular in the lungs, lymph nodes, eyes, and skin. Systemic treatment for cutaneous sarcoidosis can be used for large disfiguring lesions, generalized involvement, or recalcitrant lesions that did not respond to topical therapy. CASE PRESENTATIONS We report three ...

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Disseminated granuloma annulare (DGA) is an inflammatory disease that tends to follow a chronic course and is resistant to multiple treatments. We report the case of a 80-year-old woman with asymptomatic lesions that had developed 3 years earlier. The lesions initially developed on the arms, later spreading to the abdomen, back, and legs, and improved during the summer months. The patient had u...

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ژورنال

عنوان ژورنال: BMC Dermatology

سال: 2002

ISSN: 1471-5945

DOI: 10.1186/1471-5945-2-5